DIROHEART Tablet

COMPOSITION: Diroheart-SS For small size dogs upto 5.6 kgs Each chewable tablet contains: Ivermectin ……..……………………..………..34.0 mcg PyrantelPamoate Equivalent to Pyrantel USP……………….28.5 mg Excipients………………………………………………….q.s. Diroheart-M For medium size dogs upto 12-22 kgs Each chewable tablet contains: Ivermectin BP……………………..……..……….136 mcg PyrantelPamoate Equivalent to Pyrantel USP……………………114 mg Excipients…………………………………………………….. q.s. Diroheart-S For small size dogs upto 11 kgs Each chewable tablet contains: Ivermectin BP………………………………..……….68 mcg PyrantelPamoate Equivalent to Pyrantel USP………………………..57 mg Excipients……………………………………………………… q.s. Diroheart-L For large size dogs upto 23-45 kgs Each chewable tablet contains: Ivermectin BP……………………………….…..….272 mcg PyrantelPamoate Equivalent to Pyrantel USP………..…………..227 mg Excipients……………………………………………………… q.s. INDICATION: For use in dogs to prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilariaimmitis) for a month (30 days) after infection and for the treatment and control of ascarids (Toxocaracanis, Toxascarisleonina) and hookworms (Ancylostomacaninum, Uncinariastenocephala, Ancylostomabraziliense). DOSAGE & ADMINISTRATION: Dosage: DIROHEART (ivermectin/pyrantel) tablets should be administered orally at monthly intervals at the recommended minimum doselevel of 6 mcg of ivermectin per kilogram (2.72 mcg/lb) and 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg/lb) of body weight.The recommended dosing schedule for prevention of canine heartworm disease and for the treatment and control of ascarids andhookworms is as follows:

DOGS	TABLETS	CONTENT	CONTENT
Body wt (in KG)	Month	Ivermectin	Pyrantel
Upto 5.6 kg	1	34 mcg	28.5 mg
Upto 11	1	68 mcg	57 mg
12-22 kg	1	136 mcg	114 mg
23-45 kg	1	272 mcg	227 mg

DIROHEART is recommended for dogs 6 weeks of age and older. For dogs over 45 kgs the appropriate combination of these tablets must be given.