Closan-50

Closan-50

Closantel 5% injection solution

Ingredients

In each 1 ml of solution:

• Closantel (as sodium dihydrate) – 50 mg

Description

Closantel is a synthetic antiparasitic drug. Liver fluke, blood-sucking nematodes, and larval stages of some arthropods has a high impact on.

• Mechanism: blocks mitochondrial oxidative phosphorylation, halts ATP synthesis, disrupts the energy metabolism of the parasite, and ultimately causes it to die.

Instructions for use

In large animals and sheep:

• Liver and intestinal parasites: Fasciola hepatica, Fasciola gigantica, Haemonchus contortus, Haemonchus placei, Bunostomum phlebotomum, Oesophagostomum radiatum, Strongyloides papillosus

• In large horned animals: Hypoderma bovis

• In sheep: Paramphistomum spp., Chabertia ovina, Oestrus ovis

Contraindications

• Hypersensitivity to Closantel

• Not for intravenous or intramuscular injection.

• Not for use in lactating cows and sheep, in the last trimester of pregnancy and within one year of first calving.

Side effects

• Hyperacute anaphylactic reaction in large animals

• Allergic reactions

• Overdose: blurred vision or blindness, loss of appetite, coordination disorders, weakness

Dosage and administration method

Subcutaneously applied:

• Large cattle <200 kg and sheep: 1 ml / 10 kg live weight

• Large horned animal 200–400 kg: 20 ml

• Large cattle >400 kg: 20 ml + 5 ml for each additional 100 kg

• Maximum 20 ml per injection site

Withdrawal time

• For meat: 77 days

Packaging

• 100 ml glass vial